应用3D大脑类器官研究人类神经发育和疾病

Studying Human Neurodevelopment and Diseases Using 3D Brain Organoids

很多人对医疗事业的未来,都存在这样一种憧憬:当身上的组织器官出现问题时,人们可以在体外培养新鲜健康的相同组织器官用于移植。其实在当下,类器官的出现就是这种技术的成果体现。

Brain organoids are self-assembled three-dimensional aggregates generated from pluripotent stem cells with cell types and cytoarchitectures that resemble embryonic human brain.The technology of 3D brain organoid and its potential applications are reviewed.