摘要
Dear Editor,Since the outbreak of COVID-19 at the end of 2019,its causative agent SARS-Co V-2 has been spreading around the world for one and half a year.During the long global circulation of SARS-Co V-2,mutations in the viral genome gradually emerged and accumulated。
基金
supported by the National Key Research and Development Project of China(2020YFC0842200,2020YFA0707801,and 2021YFC0863300)
the National Natural Science Foundation of China(No.82041044)
supported by the National Science Fund for Distinguished Young Scholars(81925025)
the Innovative Research Group(81621005)from the NSFC
the Innovation Fund for Medical Sciences(2019-I2M-5-049)from the Chinese Academy of Medical Sciences。