新型微流控芯片在循环肿瘤细胞富集与鉴定中研究进展

Advances in new microfluidic chips for enrichment and detection of circulating tumor cells

微流控芯片以高捕获、高回收、微流可控、易于集成化等特点, 在循环肿瘤细胞研究中备受关注。微流控体系分选富集循环肿瘤细胞根据捕获原理主要包括依赖生物亲和标签微流控芯片、依赖物理特性免标签微流控芯片和依赖生物亲和与物理特性集成化法微流控芯片法等。

Due to the characteristics such as high capture,high recovery and precise control with fluid,the microfluidic chip has attracted much attention in the research field of circulating tumor cells(CTCs).The developed microfluidic system mainly included three types based on the captured principles such as biological affinity tag microfluidic chip,free label microfluidic chip and rely on biological affinity with the physical properties of integrated microfluidic chip.