摘要
静息态功能磁共振成像(resting-state functional magnetic resonance imaging,rs-fMRI)研究已被广泛应用于帕金森病(Parkinson's disease,PD)等神经退行性疾病的病理生理分析。帕金森患者的症状包括运动症状及非运动症状,辅助运动区(supplementary motor area,SMA)与帕金森病的病理生理有关。在这篇综述中,笔者总结了PD患者有关SMA区的rs-fMRI研究,反映了大脑网络重组与适应的变化,以跟踪和预测帕金森病的进展。
Resting functional magnetic resonance imaging(rs-fMRI)has been extensively applied to analyze the pathophysiology of neurodegenerative disorders such as Parkinson's disease(PD).The symptoms of patients with Parkinson's disease include motor symptoms and non-motor symptoms.Supplementary motor area(SMA)is related to the pathophysiology of Parkinson's disease.In this review,we summarize rs-fMRI studies related to SMA in PD patients,reflecting changes in brain network reorganization and adaptation to track and predict the progression of Parkinson's disease.
作者
杨文蕊
陈红日
李青润
杨黎
张洪英
YANG Wenrui;CHEN Hongri;LI Qingrun;YANG Li;ZHANG Hongying(Graduate School of Dalian Medical University,Dalian 116044,China;Department of Radiology,Subei People's Hospital of Jiangsu Province,Yangzhou 225001,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2021年第11期90-93,共4页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金(编号:81471642)。
关键词
功能磁共振成像
帕金森病
辅助运动区
功能连接
脑网络
functional magnetic resonance imaging
Parkinson's disease
supplementary motor area
functional connection
brain network