帕金森病辅助运动区静息态脑网络功能磁共振研究进展

Research progress of functional magnetic resonance imaging of resting brain network in supplementary motor area of Parkinson's disease

静息态功能磁共振成像(resting-state functional magnetic resonance imaging,rs-fMRI)研究已被广泛应用于帕金森病(Parkinson's disease,PD)等神经退行性疾病的病理生理分析。帕金森患者的症状包括运动症状及非运动症状,辅助运动区(supplementary motor area,SMA)与帕金森病的病理生理有关。在这篇综述中,笔者总结了PD患者有关SMA区的rs-fMRI研究,反映了大脑网络重组与适应的变化,以跟踪和预测帕金森病的进展。

Resting functional magnetic resonance imaging(rs-fMRI)has been extensively applied to analyze the pathophysiology of neurodegenerative disorders such as Parkinson's disease(PD).The symptoms of patients with Parkinson's disease include motor symptoms and non-motor symptoms.Supplementary motor area(SMA)is related to the pathophysiology of Parkinson's disease.In this review,we summarize rs-fMRI studies related to SMA in PD patients,reflecting changes in brain network reorganization and adaptation to track and predict the progression of Parkinson's disease.