浙江省血脂异常不同诊断切点患病情况及心血管病风险分析

Investiagtion of the prevalence of dyslipidemia and cardiovascular risk with different cutoff points in Zhejiang province

目的了解浙江省血脂升高和边缘升高不同诊断切点的患病及10年心血管病风险分布情况。方法分层整群抽样方法调查2015至2016年浙江省35~75岁常住居民,采用问卷调查、体格检查和生化检测,调查血脂升高和边缘升高情况并计算10年心血管病风险情况。结果共调查常住居民40751人,其中血脂异常患者15027人(患病率36.9%,标化患病率34.6%),血脂升高和血脂边缘升高者分别为12869人(患病率31.6%,标化患病率29.4%)和13810人(患病率33.9%,标化患病率33.1%)。血脂异常患者的10年心血管病风险为极高危1.0%、高危43.3%、中危24.4%和低危31.3%,而血脂升高和血脂边缘升高者分别为0.7%、42.9%、24.9%、31.5%和0.7%、22.9%、29.0%、47.4%。结论浙江省35~75岁人群血脂异常和血脂边缘升高患病率较高,10年心血管病风险为高危比例较高,应在重点关注血脂升高人群的基础上,加强对LDL-C边缘升高患者的管理。

Objective A survey was conducted to describe the prevalence of hyperlipidemia and borderline hyperlipidemia and the distribution of 10-years cardiovascular disease risk in Zhejiang. Methods 35-75 years-old residents were surveyed by a stratified multistage cluster sampling method in Zhejiang province, who were underwent questionnaire, physical examination and lab test. Prevalence of hyperslipidemia,and borderline hyperlipidemia were reported and 10 yearscardiovascular risk were assessed. Results A total of 40 751 residents were investigated. The cases [prevalence(standardized rate)] of dyslipidemia, hyperslipidemia, and borderline hyperlipidemia were 15027 [36.9%(34.6%)], 12 869 [31.6%(29.4%)] and 13 810 [33.9%(33.1%)]. The proportion of very high-,high-and medium-10-years cardiovascular risk among dyslipidemia patients were 1.0%, 43.3%, 24.4%and 31.3%, while those among subjects with hyperlipidemia and borderline hyperlipidemia were 0.7%,42.9%, 24.9%, 31.5% and 0.7%, 22.9%, 29.0%, 47.4% respectively. Conclusion There are a high prevalence of dyslipidemia and borderline hyperlipidemia among residents aged 35 to 75 years-old in Zhejiang province. The proportion with high 10-years cardiovascular risk are relatively high, and should be further managed, especially for those with borderline hyperdemia.