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cN0期甲状腺乳头状微小癌中央区淋巴结转移危险影响因素的分析 被引量:1

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摘要 目的探讨肿瘤分期(TNM)cN0期甲状腺乳头状微小癌(Papillary Thyroid Microcarcinoma,PTMC)分析患者的临床病理变化特征,并探讨可能会影响中央区淋巴转移的影响因素。方法选取了88位从2017年1月至2019年12月,在佛山第二人民医院接受首次治疗的cN0期PTMC患者的资料,进行回顾性分析,通过用χ^(2)检验,多因素Logistic回归模型分析患者的中央区淋巴结转移的危险影响因素。结果cN0期PTMC患者中央区淋巴结转移率为34.1%。单因素模型分析显示PTMC患者肿瘤直径>0.5 cm、多灶癌、包膜肿瘤侵犯其中央区淋巴结转移率是PTMC患者中央区淋巴结转移的影响因素(P<0.05)。利用多因素Logistic回归数据结果最终分析得出,PTMC患者中央区域淋巴结转移的危险影响因素就是多灶癌。结论对于有多灶癌这类重要临床病理特征和危险因素的cN0期PTMC患者,建议在进行切除原发灶的同时,同时,还应当根据患者情况进行预防性的中央区域淋巴结清扫术。
出处 《大医生》 2021年第18期75-77,共3页 Doctor
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  • 1ZHURui-sen YUYong-li LUHan-kui LUOQuan-yong CHENLi-bo.Clinical study of 312 cases with matastatic differentiated thyroid cancer treated with large doses of ^(131)I[J].Chinese Medical Journal,2005(5):425-428. 被引量:10
  • 2American Thyroid Association (ATA) Guidelines Taskforce on Thy- roid Nodules and Differentiated Thyroid Cancer, Cooper DS, Doherty GM, et al. Revised American thyroid association manage- ment guidelines for patients with thyroid nodules and differentiat- ed thyroid cancer[J]. Thyroid, 2009, 19(11):1167-1214.
  • 3Haugen BR, Alexander EK, Bible KC, et al. 2015 American thyroid as- sociation management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid as- sociation guidelines task force on thyroid nodules and differentiat- ed thyroid cancer[J]. Thyroid, 2016, 26(1):1-133.
  • 4Tuttle RM, Haddad RI, Ball DW, et al. Thyroid carcinoma, version 2.2014[J]. J Natl Compr Canc Netw, 2014, 12(12):1671-1680.
  • 5Xing MZ. Molecular pathogenesis and mechanisms of thyroid can- cer[J]. Nat Rev Cancer, 2013, 13(3):184-199.
  • 6De Biase D, Gandolfi G, Ragazzi M, et al. TERT promoter mutations in papillary thyroid microcarcinomas[J]. Thyroid, 2015, 25(9):1013- 1019.
  • 7Ito Y, Miyauchi A, Inoue H, et al. An observational trial for papillary thyroid microcarcinoma in Japanese patients[J]. World J Surg, 2010, 34(1):28-35.
  • 8Ito Y, Uruno T, Nakano K, et al. An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid [J]. Thyroid, 2003, 13(4):381-387.
  • 9Xing M, Alzahrani AS, Carson KA, et al. Association between BRAF V600E mutation and recurrence of papillary thyroid cancer[J]. J Clin Oncol, 2015, 33(1):42-50.
  • 10Jiang LH, Chen C, Tan Z, et al. Clinical characteristics related to central lymph node metastasis in cN0 papillary thyroid carcinoma: a retro- spective study of 916 patients[J]. Int J Endocrinol, 2014, 2014:385787.

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