老年高血压患者发生衰弱的相关因素分析

Analysis of related factors of frailty in elderly inpatients with hypertension

目的探讨影响老年高血压患者发生衰弱的因素。方法选择住院≥65岁老年高血压患者167例为研究对象。采用Fried量表对患者进行衰弱评估,将其分为非衰弱期组109例和衰弱期组58例;收集患者一般资料和实验室检查结果并进行对比,采用多因素Logistic回归分析,分析影响老年高血压患者发生衰弱的因素。结果2组患者年龄,收缩压,患冠心病、2型糖尿病、慢性阻塞性肺疾病(COPD),多重用药情况,总胆固醇,白蛋白,血红蛋白比较,差异均有统计学意义(P<0.05)。多因素回归分析结果显示,年龄、收缩压、多重用药、COPD、白蛋白、血红蛋白为老年高血压住院患者发生衰弱的影响因素(P<0.05)。结论年龄大、多重用药、收缩压水平高,白蛋白、血红蛋白的水平低,以及患COPD的老年高血压住院患者发生衰弱的风险更大。

Objective To explore the factors of frailty in elderly inpatients with hypertension.Methods A total of 167 elderly patients with hypertension aged≥65 years were selected as the research subjects.The patients were assessed by using the Fried scale and were divided into non-frailty group(109 cases)and frailty group(58 cases)according to their frailty state.The clinical data of patients in the two groups were compared,and the multivariate Logistic regression model was used to analyze the influencing factors of frailty among elderly inpatients with hypertension.Results There were statistically significant differences in the age,systolic blood pressure,coronary heart disease,type 2 diabetes,chronic obstructive pulmonary disease(COPD),multiple medications,total cholesterol,albumin,hemoglobin between the two groups(P<0.05).The results of multivariate regression analysis showed that age,systolic blood pressure,multiple medication,COPD,albumin and hemoglobin were the influencing factors of frailty in elderly inpatients with hypertension(all P<0.05).Conclusion Higher risk of frailty is seen in elderly inpatients with hypertension who are older,use multiple medication,with high systolic blood pressureor,suffering from COPD or low levels of albumin and hemoglobin.