施旺氏细胞在麻风免疫中的作用研究现状

Research status of the role of Schwann cells in leprosy immunity

麻风分支杆菌实际无毒力,侵入人体后可在组织中大量生长繁殖,却不引发任何临床症状,麻风的皮肤、黏膜和周围神经损伤等表现主要是由机体对麻风菌的免疫应答引起。施旺氏细胞可以支持和营养神经纤维,作为麻风菌的重要寄生场所,与麻风免疫密不可分,研究意义重大。

Mycobacterium leprae is virtually non-toxic.After invading the human body,it can grow and reproduce in large quantities in the tissues but does not cause any clinical symptoms.The manifestations of skin,mucous membrane and peripheral nerve damage of leprosy are mainly caused by the immune response of the body to the leprae.Schwann cells can support and nourish nerve fibers.As an important parasitic site of leprosy bacteria,Schwann cells are closely related to leprosy immunity,and the research on these cells is of great significance.