陕西省疾控中心预防接种门诊HPV疫苗接种情况分析

HPV vaccination in the vaccination clinic of Shaanxi Provincial Center for Disease Control and Prevention

目的了解陕西省疾控中心接种门诊HPV疫苗接种情况,指导疫苗进一步合理使用。方法对2017—2019年在陕西省疾控中心门诊接种HPV疫苗接种对象的信息和疫苗接种信息进行分析。结果共分析5716名HPV疫苗接种对象信息,其中20~26.5岁组比例最大(48.97%),9~15岁组比例最小(1.12%)。九价HPV疫苗接种20~26.5岁组占比高达98.72%。双价和四价、九价HPV疫苗接种人群分布比较差异均有统计学意义(P<0.01,χ^(2)=252.85),(P<0.01,χ^(2)=258.15)。双价HPV疫苗全程接种率为88.25%(894/1013),四价HPV疫苗全程接种率为94.43%(1915/2028),差异有统计学意义(Z=-2.02,P=0.043)。结论接种对象倾向于选择高价型HPV疫苗,小年龄组人群HPV疫苗接种比例严重不足;双价和四价HPV疫苗均具有相对较高的全程接种率;下一步应加强小年龄组人群疫苗接种宣传。

Objective To understand the HPV vaccination situation in the vaccination clinic of Shaanxi Provincial Center for Disease Control and Prevention,and to guide the rational use of the vaccine.Methods The vaccination information and the information on HPV vaccine inoculated subjects in the clinic of Shaanxi Provincial Center for Disease Control and Prevention from 2017 to 2019 were analyzed.Results A total of 5716 HPV vaccination subjects were analyzed,among which the largest proportion(48.97%)was in the 20-26.5 years old group,and the smallest proportion(1.12%)was in the 9-15 years old group.The 9-valent HPV vaccination accounted for 98.72%of the 20-26.5-year-old group.There were statistically significant differences in the distribution of vaccination populations between the bivalent and quadrivalent HPV vaccines(P<0.01,χ^(2)=252.85),and between the bivalent and 9-valent HPV vaccines(P<0.01,χ^(2)=258.15).The vaccination rate of the bivalent HPV vaccine was 88.25%(894/1013),and the vaccination rate of the quadrivalent HPV vaccine was 94.43%(1915/2028).The difference was statistically significant(Z=-2.02,P=0.043).Conclusion Vaccination subjects tend to choose high-valent HPV vaccines,and the proportion of HPV vaccination in the younger age group is seriously insufficient.Both bivalent and quadrivalent HPV vaccines have relatively high overall vaccination rates.The next step should be to strengthen the vaccination publicity for younger age groups.