OCTA在视盘血管炎Ⅰ型患者中的应用

Optical Coherence Tomography Angiography in type I optic disc vasculitis

目的利用相干光层析血流成像术(OCTA)观察视盘血管炎Ⅰ型患者视盘、黄斑区血流的变化。方法回顾性病例研究。纳入确诊为视盘血管炎Ⅰ型患者及健康志愿者。分析比较视盘血管炎Ⅰ型患者视盘与黄斑区血流、视神经纤维层、视觉诱发电位的相关性,血流各区域的差异性,以及与健康人血流差异性分析。结果本研究结果显示视盘血管炎Ⅰ型患者视盘区、黄斑区血流无相关性(P>0.05)各区域血流之间存在差异性(P<0.01),视盘血流与视神经纤维层之间无相关性(P>0.05),视盘血管炎Ⅰ型患者比健康人视盘区血流显著减少(P<0.05),视盘血管炎Ⅰ型患者与健康人黄斑区血流之间无明显差异(P>0.05)。结论OCTA可以为视盘血管炎Ⅰ型患者提供客观的检查依据。

Objective To investigate the peripapillary and macular vessel density in eyes with type I optic disc vasculitis.Methods Retrospective case study.Patients diagnosed with type I optic disc vasculitis and healthy participants were enrolled.The blood flow of the optic nerve head and macula,the visual evoked potential,the retinal nerve fiber layer,and the difference of blood flow in different retinal regions in patients with type I optic disc vasculitis were assessed,and compared with those in healthy participants.Results There was no correlation between the blood flow in the optic disc area and macular area(P>0.05).There were significant differences in the blood flow at different retinal regions(P<0.01).There was no correlation between the blood flow in the optic disc and optic nerve fiber layer(P>0.05).The blood flow in patients with type I optic disc vasculitis was significantly reduced compared with healthy subjects(P<0.05),and there was no significant difference between healthy subjects and optic disc vasculitis patients in the blood flow in the macula area(P>0.05).Conclusions OCTA can provide objective examination for patients with type I optic disc vasculitis.