杭州市HIV/AIDS病例生活质量调查及影响因素分析

Quality of life and its influencing factors among people living with HIV/AIDS in Hangzhou City

目的了解杭州市艾滋病病毒感染者和艾滋病患者(HIV/AIDS)的生活质量,并分析其影响因素,为艾滋病防治提供依据。方法选择2014年1月1日—2018年6月30日杭州市现存活HIV/AIDS病例为调查对象,采用基本情况调查表收集人口学信息、医疗支出和疾病状态等资料,采用MOS-HIV量表简体中文版评估生活质量;采用多重线性回归模型分析HIV/AIDS病例生活质量的影响因素。结果调查HIV/AIDS病例2808例,其中HIV感染者1684例,AIDS患者1124例。男性2510例,占89.39%;女性298例,占10.61%。25~<40岁1531例,占54.52%。MOS-HIV量表的生理健康总分和心理健康总分分别为(53.87±6.96)分和(46.03±9.09)分。多重线性回归分析结果显示,年龄、月均收入、最近一年就医自理费用、最近一次CD4^(+)T淋巴细胞计数是生理健康和心理健康的影响因素(P<0.05)。结论杭州市HIV/AIDS病例生活质量不高;年龄、收入、治疗费用和CD4^(+)T淋巴细胞计数均可能影响HIV/AIDS病例的生活质量。

Objective To investigate the quality of life among people living with HIV/AIDS in Hangzhou City and analyze the influencing factors,so as to provide insights into the control of AIDS.Methods From 1 January 2014 to 30 June 2018,the demographic characteristics,medical expenditures and disease status were collected from HIV/AIDS patients living in Hangzhou City,and the quality of life was assessed using the simplified Chinese version of Medical Outcomes Study-HIV Health Survey(MOS-HIV).Factors affecting the quality of life were identified among HIV/AIDS patients using multivariable linear regression analysis.Results A total of 2808 HIV/AIDS patients were surveyed,including 1684 cases with HIV infections and 1124 cases with AIDS.The participants included 2510 men(89.39%)and 298 women(10.61%),and were predominantly at ages of 25 to 39 years(1531 cases,54.52%).The physical and mental health scores were 53.87±6.96 and 46.03±9.09,respectively.Multivariable linear regression analysis identified age,average monthly income,self-paid medical expenses during the past year,and the latest CD4^(+)T cell count as factors affecting physical and mental health(P<0.05).Conclusions The quality of life is low among people living with HIV/AIDS in Hangzhou City,and is associated with age,income,medical expenditures and CD4^(+)T cell count.