宫颈腺癌与宫颈鳞癌的临床病理特征及检查分析

Clinicopathological Characteristics and Examination Analysis of Cervical Adenocarcinoma and Cervical Squamous Cell Carcinoma

目的研究宫颈腺癌与宫颈鳞癌的临床病理特征及妇科检查特点。方法于我实验室宫颈腺癌和宫颈鳞癌患者样本中各随机抽取50例,作为对照组和观察组,均给予病理检查,收集患者妇科检查资料,回顾性分析两组妇科检查和病理特征。结果对照组宫颈光滑8例(16.00%),宫颈桶状增大10例(20.00%),宫颈赘生物26例(52.00%),子宫增大5例(10.00%);观察组宫颈光滑1例(2.00%),宫颈桶状增大3例(6.00%),宫颈赘生物16例(32.00%),子宫增大1例(2.00%)。两组对比,差异有统计学意义(P<0.05)。对照组肿瘤直径≥4 cm有24例(48.0%),淋巴结阳性11例(22.00%),深间质浸润33例(66.00%),脉管间隙浸润10例(20.00%);观察组肿瘤直径≥4 cm有10例(20.00%),淋巴结阳性5例(10.00%),深间质浸润19例(38.00%),脉管间隙浸润5例(10.00%)。两组对比,差异有统计学意义(P<0.05)。结论宫颈腺癌和宫颈鳞癌在临床检查和病理特征常存在一定差异,通过对比子宫和宫颈表现,能够初步分辨。同时根据淋巴结、浸润特点以及肿瘤直径,可进一步分辨指导临床治疗。

Objective To study the clinicopathological and gynecological features of cervical adenocarcinoma and cervical squamous cell carcinoma.Methods In our laboratory,50 cases of cervical adenocarcinoma and cervical squamous cell carcinoma were randomly selected as control group and observation group.Pathological examination was given,gynecological examination data were collected,and gynecological examination and pathological characteristics were analyzed retrospectively.Results In the control group,there were 8 cases(16.00%)with smooth cervix,10 cases(20.00%)with barrel enlargement of cervix,26 cases(52.00%)with cervical neoplasms,and 5 cases(10.00%)with enlarged uterus.In the observation group,there was 1 case(2.00%)with smooth cervix,3 cases(6.00%)with barrel enlargement of cervix,16 cases(32.00%)with cervical vegetation,and 1 case(2.00%)with uterine enlargement.The difference between the two groups was significant(P<0.05).In the control group,there were 24 cases(48.00%)with tumor diameter≥4 cm,11 cases(22.00%)with positive lymph nodes,33 cases(66.00%)with deep interstitial infiltration,and 10 cases(20.00%)with intervascular infiltration.In the observation group,there were 10 cases(20.00%)with tumor diameter≥4 cm,5 cases(10.00%)with positive lymph nodes,19 cases(38.00%)with deep interstitial infiltration,and 5 cases(10.00%)with vascular space infiltration.The difference between the two groups was significant(P<0.05).Conclusion Cervical adenocarcinoma and cervical squamous cell carcinoma often have certain differences in clinical examination and pathological characteristics.By comparing the appearance of uterus and cervix,it can be preliminarily distinguished.At the same time,according to the characteristics of lymph nodes,infiltration and tumor diameter,it can further distinguish and guide clinical treatment.