医用三原子氧化三蒸水联合艾普拉唑四联疗法治疗慢性胃炎伴幽门螺杆菌感染的临床效果

Clinical effect of medical triatomic oxidized tri-steamed water combined with ilaprazole quadruple therapy in the treatment of chronic gastritis complicated with Helicobacter pylori infection

目的探讨医用三原子氧化三蒸水联合艾普拉唑四联疗法治疗慢性胃炎伴幽门螺杆菌(Hp)感染的临床效果。方法选取70例慢性胃炎伴Hp感染患者,将其随机分为对照组和观察组,各35例。对照组予以艾普拉唑四联疗法治疗,观察组予以医用三原子氧化三蒸水联合艾普拉唑四联疗法治疗。比较两组的Hp根除率、临床疗效、胃肠功能指标(G-17、PGⅠ)及血清炎性因子(IL-6、CRP、TNF-α)水平。结果观察组的Hp根除率、治疗总有效率高于对照组(P<0.05)。治疗后,观察组的血清G-17、PGⅠ、IL-6、CRP、TNF-α水平低于对照组(P<0.05)。结论医用三原子氧化三蒸水联合艾普拉唑四联疗法治疗慢性胃炎伴Hp感染可明显强化临床疗效,提高Hp根除率,改善胃功能,减轻炎症反应。

Objective To investigate the clinical effect of medical triatomic oxidized tri-steamed water combined with ilaprazole quadruple therapy in the treatment of chronic gastritis complicated with Helicobacter pylori(Hp)infection.Methods Seventy patients with chronic gastritis complicated with Hp infection were selected and randomly divided into control group and observation group,with 35 cases in each group.The control group was treated with ilaprazole quadruple treatment,and the observation group was treated with medical triatomic oxidized tri-distilled water combined with ilaprazole quadruple treatment.The Hp eradication rate,clinical efficacy,levels of gastrointestinal function indexes(G-17,PGⅠ)and serum inflammatory factors(IL-6,CRP,TNF-α)were compared between the two groups.Results The Hp eradication rate and total effective rate of treatment in the observation group were higher than those in the control group(P<0.05).After treatment,the levels of serum G-17,PGⅠ,IL-6,CRP and TNF-αin the observation group were lower than those in the control group(P<0.05).Conclusion Medical triatomic oxidized tri-steamed water combined with iprazole quadruple therapy in the treatment of chronic gastritis complicated with Hp infection can significantly strengthen the clinical efficacy,increase Hp eradication rate,improve gastric function and reduce inflammatory reaction.