肿瘤靶向药及免疫检查点抑制剂相关皮肤病及诊治进展

Advances in diagnosis and treatment of cutaneous adverse events associated with tumor targeted drugs and immune checkpoint inhibitors

肿瘤靶向及免疫治疗是肿瘤治疗学的重大进展。肿瘤靶向药物及免疫检查点抑制剂的种类多、效果好,临床应用越来越广泛,但同时常引发一系列不良反应。其中,皮肤不良反应事件较为常见。不同药物引起的皮肤病不尽相同,治疗也因人而异。虽然肿瘤治疗相关皮肤反应对患者身心造成了一定影响,但同时可能预示更好的疗效。

Tumor targeted therapy and immunotherapy are important advances in tumor treatment.With numerous varieties and promising efficacy,targeted drugs and immune checkpoint inhibitors are widely used in clinical practice,which meanwhile triggers a series of adverse events.Among them,cutaneous adverse events are more common.Skin diseases caused by different drugs are distinct,and treatment varies from person to person.Although cutaneous adverse events associated with tumor treatment affect the physical and psychological health of patients,they may indicate better therapeutic effect.