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生物转化生产稀有糖醇——阿洛醇(蒜糖醇)研究进展

Research progress for biotransformation of allitol
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摘要 阿洛醇(又称蒜糖醇)是一种低热量六碳稀有糖醇,不会导致肥胖和血糖升高,适合于肥胖、糖尿病人群。此外,因其具有润肠通便等作用,在食品、医药等领域具有重要应用。同时,阿洛醇还是合成其他具有重要生理功能的D/L-型稀有糖的原料。文中介绍了阿洛醇的应用价值、生物合成方法,对生物合成阿洛醇的生物酶、生产工艺及研究进展进行了综述,并对阿洛醇的生物合成进行了展望。 Allitol is a low-calorie six-carbon rare sugar alcohol without weight or blood sugar increasing effects,which is suitable for obese and diabetic consumers.Allitol also has the effects of moistening intestines and laxative.It has important applications in food,medicine and other industries.In addition,allitol is also a raw material for the synthesis of other D/L-type rare sugars with important physiological functions.This article introduces the application values and biosynthetic method of allitol.The bio-enzymes,production process,and research progress for biosynthesis of allitol were summarized and the future for allitol biosynthesis was prospected.
作者 温鑫 宁宇航 林慧彬 任一林 林建群 林建强 WEN Xin;NING Yuhang;LIN Huibin;REN Yilin;LIN Jianqun;LIN Jianqiang(State Key Laboratory of Microbial Technology,Shandong University(Qingdao),Qingdao 266237,China;Shandong Academy of Chinese Medicine,Jinan 250014,China;Qingdao Longding Biotech Limited Company,Qingdao 266108,China)
出处 《食品与发酵工业》 CAS CSCD 北大核心 2022年第1期286-291,共6页 Food and Fermentation Industries
基金 国家重点研发计划项目(2017YFC1701502、2017YFC1701504、2017YFC1702701) 泰山学者工程(ts201511107) 中央本级重大增减支项目(2060302) 济南市农业应用技术创新计划项目(CX202112) 道地药材生态种植及质量保障项目 中国博士后科学基金项目(2021M701994)。
关键词 稀有糖醇 阿洛醇(蒜糖醇) 核糖醇脱氢酶 甲酸脱氢酶 生物转化 rare sugar alcohol allitol ribitol dehydrogenase formate dehydrogenase biotransformation
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