PCI术后患者心肺运动试验医学参考值的初步探索

Preliminary study on the medical reference value of cardiopulmonary exercise test in patients after PCI

目的探讨经皮冠状动脉介入治疗(PCI)术后患者心肺运动试验参数及其变化规律,以期建立PCI术后患者心肺运动试验正常参考值范围。方法选取解放军总医院心血管内科2017年6月~2019年6月1149例行PCI的冠心病患者,采用心肺运动测试系统进行心肺运动试验,对不同年龄段的心肺运动试验各项参数进行分析比较。结果PCI术后患者心肺运动试验各项参数中:峰值功率(Wmax)、峰值摄氧量(VO_(2)max)、峰值公斤摄氧量(VO_(2)max/kg)、无氧阈时公斤摄氧量(VO_(2)AT/kg)、峰值氧脉(O_(2)pulse)、峰值呼吸交换率(RERmax)、心率储备(HRR)、呼吸储备(BR)随着年龄的增加而减少,二氧化碳通气当量(VE/VCO_(2))随着年龄的增加而增加。结论根据患者不同年龄段特点来进行适宜的运动试验,从而在获得准确数据的同时,保证运动试验的安全性。本研究首次提出PCI术后患者心肺运动试验参考值应用方程,为心肺运动试验检查的精准进行提供了可靠依据。

Objective To explore the parameters of cardiopulmonary exercise test(CPET)and their changes in patients after PCI in order to establish the normal reference range of CPET.Methods The cardiopulmonary exercise test was performed in 1149 patients after PCI,the parameters of cardiopulmonary exercise test in different ages were analyzed and compared.Results Among the parameters of cardiopulmonary exercise test after PCI:With the increase of age,Wmax,VO_(2)max,VO_(2)max/kg,O_(2)pulse,RER,HRR,BR were all decreased,VE/VCO_(2)was increased.Conclusion It is of great significance to master the medical reference value of each age group.Appropriate exercise test should be carried out according to the characteristics of different age groups of patients,so as to obtain accurate data and ensure the safety of exercise test.This study is the first time to put forward the application equation of reference value of cardiopulmonary exercise test for patients after PCI,which provides a reliable basis for getting data accurately of cardiopulmonary exercise test.