行髋关节置换的股骨头坏死患者病因学特征

Etiology charistics analysis of cases with femoral head osteonecrosis for total hip arthoplasty

目的探讨股骨头坏死患者的流行病学及发病的相关危险因素,为股骨头坏死的防治提供依据。方法选取2017年1月~2019年12月,首次在解放军总医院行人工全髋关节置换术的1052股骨头坏死患者住院资料;按性别分组,分析不同侧别、民族、地区及病因构成比,从发病年龄分布方面分析发病特征,运用构成比、χ^(2)检验、秩和检验等方法进行汇总统计分析。结果性别分组中发病侧别、病因的差异均有统计学意义(P<0.05),民族、地区构成的差异均无统计学意义;各年龄组段内性别差异没有统计学意义(P>0.05);男性组与女性组中51~60岁年龄段构成比均最高。结论股骨头坏死病因构成中特发性所占比例最高,对本病认识水平有待进一步提高。男性已知原因以酒精为主要病因、女性主要由应用激素引起。

Objective Investigate the epidemiology and risk factors of avascular necrosis of the femoral head in order to provide evidence for prevention and treatment of avascular necrosis of the femoral head.Methods the related information forms were designed to collect the data of 1052 patients with femoral head necrosis undergoing total hip replacement for the first time in general hospital of Liberation Army from January 2017 to December 2019.According to gender,side,nationality,provience and etiological factor were analyzed,and the incidence of the disease was analyzed from the age distribution of the disease.Constitution ratio,X 2 test and rank sum test were used for statistical analysis.Results there were significant differences in both sides and etiological factors in the gender groups(P<0.05).There was no significant difference in different ethnic and region groups,and there was no statistical difference between different age groups.Patients with 51~60 years old age were most.Conclusions the proportion of Idiopathic is the highest in the etiology of osteonecrosis of the femoral head,and the level of understanding of this disease needs to be further improved.Alcohol is the main cause of male known causes,and women are mainly caused by the use of hormones.