全胸腔镜肺叶切除术与小切口开胸术治疗早期非小细胞肺癌患者的效果比较

Comparison of effects of total thoracoscopic lobectomy and small incision thoracotomy in treatment of patients with early non-small cell lung cancer

目的:比较全胸腔镜肺叶切除术与小切口开胸术治疗早期非小细胞肺癌(NSCLC)患者的效果。方法:选择90例早期NSCLC患者为研究对象。按随机数字表法分为观察组和对照组各45例,观察组行全胸腔镜肺叶切除术治疗,对照组行小切口开胸术治疗。比较两组围术期指标水平和术后并发症发生率。结果:观察组术中出血量为(96.42±28.41)mL、术后引流量为(231.45±42.65)mL,分别少于对照组的(159.42±37.65)mL、(402.78±82.65)mL,差异有统计学意义(P<0.05);观察组术后住院时间为(9.11±1.96)d、疼痛时间为(3.72±1.05)d,分别短于对照组的(13.78±4.85)d、(5.32±1.48)d,差异有统计学意义(P<0.05);两组淋巴结清扫数目、手术时间比较,差异均无统计学意义(P>0.05);观察组术后并发症发生率为8.89%(4/45),低于对照组的28.89%(13/45),差异有统计学意义(P<0.05)。结论:全胸腔镜肺叶切除术治疗早期NSCLC患者可改善围术期指标水平,降低术后并发症发生率,其效果优于小切口开胸术治疗效果。

Objective:To compared effects of total thoracoscopic lobectomy and small incision thoracotomy in treatment of patients with early non-small cell lung cancer(NSCLC).Methods:90 patients with early NSCLC who visited the hospital from January 2019 to December 2020 were selected as the research objects.According to the random number table,they were divided into observation group(45 cases)and control group(45 cases).The observation group was treated with VATS lobectomy,while the control group was treated with small incision thoracotomy.The perioperative index levels and the incidence of postoperative complications were compared between the two groups.Results:The intraoperative blood loss of the observation group was(96.42±28.41)mL,and the postoperative drainage volume was(231.45±42.65)mL,which were less than the control group of(159.42±37.65)mL and(402.78±82.65)mL,respectively,and the differences were statistically significant(P<0.05).The postoperative hospitalization time in the observation group was(9.11±1.96)days,and the pain time was(3.72±1.05)days,which were shorter than the control group of(13.78±4.85)days and(5.32±1.48)days,respectively,and the differences were statistically significant(P<0.05).There were no significant differences in the number of lymph node dissected and the operation time between the two groups(P>0.05).The postoperative complication rate in the observation group was 8.89%(4/45),which was lower than 28.89%(13/45)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Total thoracoscopic lobectomy can improve the levels of the perioperative indicators and reduce the incidence of postoperative complications in the patients with early NSCLC.Moreover,it is superior to small incision thoracotomy.