钛夹辅助结肠镜定位用于结直肠癌手术的疗效及安全性分析

Clinical analysis of the efficacy and safety of titanium clip assisted lesion-location under colonoscopy for colorectal cancer surgery

目的分析钛夹辅助结肠镜定位用于结直肠癌手术的疗效及安全性。方法回顾性研究2017年3月至2020年3月接受手术治疗的121例结直肠癌患者临床资料,按照不同定位方式分为单纯组(单纯结肠镜定位,53例)、联合组(钛夹辅助结肠镜定位,68例)。采用SPSS 24.0统计分析软件,围术期计量资料以(x±s)表示,采用独立样本t检验;定位效果、并发症等计数资料用χ^(2)检验。P<0.05为差异有统计学意义。结果联合组右半结肠、左半结肠、乙状结肠的定位与实际肿瘤位置符合率(100.0%、100.0%、95.2%)均比单纯组(73.3%、73.3%、72.2%)高(P<0.05);联合组手术时间、术中探查病灶时间短于单纯组,术中出血量高于单纯组(P<0.05);术后并发症发生率两组差异无统计学意义(P>0.05)。结论钛夹辅助结肠镜定位用于结直肠癌手术中可准确定位肿瘤部位,指导穿刺孔位置及手术切口的选择,缩短手术时间,且安全性高。

Objective To analyze the efficacy and safety of Titanium clip-assisted lesion-location under colonoscopy for colorectal cancer surgery.Methods The clinical data of 121 patients with colorectal cancer underwent surgical treatment from March 2017 to March 2020 were analyzed retrospectively.They were divided into the simple group(simple colonoscopy,n=53 cases),and the combined group(titanium clip assisted lesion-location under colonoscopy,n=68 cases),Statistical analysis were performed by using SPSS24.0 software,the perioperative data were expressed as,the difference between the two groups were examined by using t test.The locating effect and complications were examined by usingχ^(2) test.A P value of<0.05 was considered as statistically significant difference.Results The concordance rate of the location with the actual tumor location in the combined group was higher than that of the simple group in the right colon,left colon,and sigmoid colon(100.0%,100.0%,95.2%vs.73.3%,73.3%,72.2%respectively,P<0.05).The average operation time and intraoperative detecting time of the combined group were much shorter than those of the simple group respectively,and the intraoperative blood loss was lower than that of the simple group(P<0.05).There was no significant difference between two groups in terms of the incidence of perioperative complications(P>0.05).Conclusion Titanium clips assisted lesion-location under colonoscopy for colorectal cancer surgery could accurately locate the tumor site,for guiding the location of Trocars and the selection of surgical incision,with shortened the operation time and more safety.