结直肠癌肝转移多阶段机制研究进展

Research progress on multi-stage mechanism of colorectal cancer liver metastasis

结直肠癌是我国常见恶性肿瘤类型之一,且很多患者在确诊时就已经发生了肝脏转移,这也是结直肠癌高死亡率的主要原因。因此研究结直肠癌肝转移(CLM)的机制具有重要意义。但目前肝转移具体机制尚不明确,本文将从细胞分子水平对肝转移的机制进行综述,期望为结直肠癌肝转移的研究治疗探索新的思路方法。

Colorectal cancer is one of the common types malignant tumor types in China,of malignant tumors in my country,and many patients have already experienced liver metastasis when they are diagnosed,which is also the main reason for the high mortality rate of colorectal cancer.Therefore,it is important to study the mechanism of colorectal cancer liver metastasis(CLM).However,the specific mechanism of liver metastasis is not clearstill unclear at present.This article will review the mechanism of liver metastasis from the cellular and molecular level,hoping to explore new ideas and methods for the research and treatment of colorectal cancer liver metastasis.