五皮饮联合呋塞米治疗肝硬化失代偿期腹腔积液的疗效

Observation of curative effect ofWupiyin combined with furosemide in the treatment of peritoneal effusion of decompensated liver cirrhosis

目的探讨五皮饮联合呋塞米治疗肝硬化失代偿期腹腔积液的疗效。方法选取2018年11月至2019年11月本院收治的肝硬化失代偿期腹腔积液患者64例,根据盲抽法分为观察组和对照组,各32例。在对症治疗基础上,对照组予以呋塞米注射液治疗,观察组在对照组基础上给予五皮饮加减治疗。比较两组临床疗效、肝功能指标。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗20 d后,两组AST、ALT水平均低于治疗前,ALB水平高于治疗前,且观察组均优于对照组,差异有统计学意义(P<0.05)。结论五皮饮联合呋塞米治疗肝硬化失代偿期腹腔积液疗效显著,可改善患者肝功能。

Objective To investigate the effect of Wupiyin combined with furosemide in the treatment of peritoneal effusion during decompensation of cirrhosis.Methods 64 patients with decompensated peritoneal cirrhosis from November 2018 to November 2019 in our hospital were selected and they were divided into observation group and control group according to blind sampling,with 32 cases in each group.On the basis of symptomatic treatment,the control group was treated with furosemide injection,the observation group was given Wupiyin addition and subtraction treatment on the basis of the control group.The clinical efficacy and liver function indexes were compared between two groups.Results The total clinical effective rate of the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).After 20 d of treatment,the AST and ALT levels of the two groups were lower than before treatment,and the ALB level was higher than before treatment,the observation group was better than the control group,the difference was statistically significant(P<0.05).Conclusion Wupiyin combined with furosemide is effective in the treatment of decompensated peritoneal effusion of liver cirrhosis,which can improve the liver function of patients.