脑胶质瘤患者手术前后近期心境障碍的临床观察

Clinical observation of recent mood disorders in patients with glioma before and after surgery

目的探究脑胶质瘤患者手术前后近期心境障碍的临床情况。方法回顾性分析2018年3月至2020年3月本院神经外科收治的71例手术治疗的脑胶质瘤患者的临床资料,比较患者手术前后抑郁、焦虑和躁狂情况,并进行多元线性回归分析影响患者术前抑郁评分的主要因素。结果术后,患者汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、倍克-拉范森躁狂量表(BRMS)评分均低于术前,但差异无统计学意义;高级别、额颞叶患者HAMD评分均低于术前(P<0.05);多元线性回归分析结果显示,术前HAMD评分与家庭收入高低呈负相关(P<0.05)。结论脑胶质瘤患者手术前后易出现心境障碍情况,其中抑郁情况较常见,而抑郁的发生可能与胶质瘤生长部位等因素有关,且术前抑郁情况受家庭收入影响较大,家庭收入为其独立危险因素。

Objective To investigate the clinical situation of recentmood disorders in patientswith glioma before and after surgery.Methods The clinical data of 71 patients with glioma who were treated in the neurosurgery department of our hospital from March 2018 to March 2020 were retrospectively analyzed,compare the situation of depression,anxiety and mania before and after surgery,and carry out multiple linear regression analysis to analyze the main factors affecting the preoperative depression score of patients.Results After surgery,Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA),Beech-Lafansen Mania Scale(BRMS)score were lower than before surgery,but the difference was not statistically significant;HAMD score of high-level,frontotemporal patients were lower than before surgery;the results of multiple linear regression analysis showed that preoperative HAMD score was negatively correlated with family income.Conclusion Patients with glioma are prone to mood disorders before and after surgery,depression is more common,and the occurrence of depression may be related to glioma growth site and other factors,and preoperative depression is greatly affected by family income,family income is an independent risk factor.