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间充质干细胞外泌体的特点及其在宫腔粘连中的研究进展 被引量:4

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摘要 外泌体作为细胞分泌的一种微囊泡,是间充质干细胞(MSCs)旁分泌作用的主要方式,在细胞间信号传递和物质运输中发挥重要的桥梁作用,其内携带的多种生物活性因子,如miRNA等可参与靶细胞的多种生理病理过程。MSCs来源的外泌体通过逆转上皮间质转化、促进细胞增殖与血管形成和调节免疫平衡等机制参与子宫内膜纤维化的进展。本文将通过阐述MSCs外泌体的基本特点,分析其在宫腔粘连(IUA)发生发展中的作用,为临床治疗IUA提出新的视角和思路。
作者 李晓 段华
出处 《现代妇产科进展》 CSCD 北大核心 2022年第2期150-153,共4页 Progress in Obstetrics and Gynecology
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