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大剂量地塞米松治疗成人原发性免疫性血小板减少症合并糖尿病的有效性及安全性 被引量:1

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摘要 目的:综合分析大剂量地塞米松治疗成人原发性免疫性血小板减少症(ITP)合并糖尿病的有效性及安全性。方法:选取ITP合并糖尿病患者共48例,按照入院顺序分为对照组(24例)和实验组(24例),其中对照组应用门冬胰岛素+甘精胰岛素+强的松联合治疗方法,实验组门冬胰岛素+甘精胰岛素+大剂量地塞米松治疗方法。采用统计学分析两组不良反应(血糖上升、腹胀不适)发生率、临床治疗效果以及治疗前后CD4^(+)CD25^(+)水平、空腹血糖(FPG)水平、血小板计数(PLT)。结果:两组ITP合并糖尿病患者的不良反应(血糖上升、腹胀不适)发生率、临床治疗效果差异显著(P<0.05),两组ITP合并糖尿病患者治疗前CD4^(+)CD25^(+)水平、FPG水平、PLT比较无差异(P>0.05),治疗后两组ITP合并糖尿病患者治疗前CD4^(+)CD25^(+)水平、FPG水平、PLT比较差异显著(P<0.05)。结论:大剂量地塞米松治疗成人ITP合并糖尿病的有效性及安全性高。
作者 周文峰
出处 《北方药学》 2021年第7期181-182,共2页 Journal of North Pharmacy
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