抗菌聚己内酯/聚乳酸纳米纤维膜的制备及其性能

Synthesis and Properties of AntibacterialPolycaprolactone/Polylactic Acid Nanofiber Membrane

将聚乳酸和聚己内酯共混,通过添加卤胺小分子(DCDMH)作为抗菌有效成分,制备了具有优异抗菌性能的复合纳米纤维膜。采用扫描电子显微镜(SEM)和傅里叶红外光谱(FT-IR)对样品的物化性能进行分析;对样品的储藏稳定性、降解性能以及抗菌性能进行了测试。结果表明,复合纳米纤维膜具有优异的抗菌性能,可在10 min内完全杀灭数量级为7的大肠杆菌O157:H7和金黄色葡萄球菌;同时样品在30 d内具有良好的储藏稳定性和降解性能。卤胺改性复合纳米纤维膜不但拓宽了卤胺抗菌剂的应用领域,同时为可降解材料的抗菌性能研究提供了新的思路和发展方向。

Polycaprolactone and polylactic acid were mixed firstly,and one kind of N-halamine micro molecules(MCDMH)was added in the above solution to prepare composited nanofiber membranes with excellent antibacterial properties.The physical and chemical structures of the nanofiber membranes were characterized by scanning electron microscopy(SEM)and Fourier transform infrared spectroscopy(FT-IR),and the storage stability,degradation and antibacterial properties of each sample were tested and analyzed.The results shows that the composited nanofiber membranes possess good antimicrobial properties,and inactivated 100%of E.coli O157:H7 and S.aureus with 7.57 and 7.35 logs reductions within 10 min of contact,respectively.The composited nanofiber membranes showed good storage stability and degradation properties within 30 days.This N-halamine modified nanofiber membranes broadened the application of N-halamine antibacterial agents,and provided a new horizon and direction for antibacterial modification of degradation materials.