血清尿酸在心血管疾病中的作用机制研究进展

Research progress on the mechanism of serum uric acid in cardiovascular disease

目的尿酸是人体嘌呤核苷酸代谢的最终产物。研究发现,血清尿酸(SUA)水平的升高除了与痛风发作有关,同时还参与高血压、冠心病、心力衰竭、心房颤动等心血管疾病的发生,甚至对血栓相关性疾病也有一定诊疗价值。文章就SUA与心血管疾病相关性研究的最新进展进行综述。

Uric acid is the final product of human purine nucleotide metabolism.Studies have found that the increase in serum uric acid(SUA)levels is not only related to gout attacks,but also involved in the occurrence of cardiovascular diseases such as hypertension,coronary heart disease,heart failure,atrial fibrillation,and even has a certain diagnostic value for thrombosis-related diseases.This article reviews the latest progress in the study of the correlation between SUA and cardiovascular diseases.