抗生素耐药与临床用药对照研究

A Comparative Study of Antibiotic Resistance and Clinical Ues

目的分析2014年-2019年微生物室分离的常见细菌及药敏结果,观察细菌种类及其对常用抗生素的耐药情况,了解不同菌种的耐药特点,指导临床医师合理使用抗菌药物,减少细菌耐药菌株的发生。方法根据微生物室细菌培养及药敏结果,筛选出符合条件的数据,计算各种细菌对各种抗抗生素的耐药率,统计每年抗生素使用排名。结果 2014年-2019年共分离出非重复细菌8177株,检出病原菌的前三位分别为肺炎克雷伯菌、大肠埃希菌和表皮葡萄球菌。结论虽然抗菌素耐药问题无法避免,但规范的抗菌药物使用、药学监管部门的质控可以缓解抗生素耐药压力。

Objective Retrospectively analyze the common bacteria and drug sensitivity results islated from the microbiology chamber of our hospital from 2014 to 2019,observe the bacterial species and their drug resistance to commonly used antibiltics, understand the characteristics of drug resistance of different strains in our hospital, guide clinicians to rationally use antibiotics.Methods According to the results of bacterial culture and drug sensitivity in the microbiology laboratory of our hospital, eligible date were screened out, the drug resistance rates of various bacteria to various antibiotics were calculated, and the ranking of antibiotic use per year was calculated.Results A total of 8177 non-repeating bacteria strains were isolated from our hospital from 2014 to 2019,and the top three pathogens were Klebsiella pneumoniae, Escherichia coli and Staphylococcus epidermidis.Conclusions Although the problem of antibiotic resistance cannot be avoided, standardized use of antibiotics and quality control by pharmaceutical regulatory departments can alleviate the pressure of antibiotic resistance.