种植体周围炎的免疫应答机制及其影响因素的研究进展

Research progress of the mechanism of immune response and influencing factors of peri-implantitis

种植体周围炎是种植体周围以黏膜炎症和骨吸收等软硬组织损伤为临床表现的一类菌斑相关性的炎性疾病,是导致种植修复失败的重要并发症。近年来,大量研究报道免疫应答在种植体周围炎发病及进展过程中起到重要作用,通过免疫调控可以影响种植体周围炎的发展与防治。该文就种植体周围炎中免疫应答的相关研究进展作一综述。

Peri-implantitis is a kind of plaque related inflammatory disease around dental implant,which is clinically characterized by mucositis,bone absorption and other soft and hard tissue damages,and is an important complication leading to the failure of dental implant.In recent years,a great number of studies have reported that immune response plays an important role in the pathogenesis and progression of peri-implantitis.Immunomodulation of local microenvironment can affect the development and prevention and treatment of peri-implantitis.This article reviewed the related research progress of immune response,mechanism and influencing factors of peri-implantitis.