光生物调节的基本原理及其在皮肤科的应用

Basic principles of photobiomodulation and its application in dermatology

光生物调节,亦称光调作用,指利用多种光源的低功率强度光来引发对机体非热损伤的光物理和光化学调节作用。光生物调节与光的波长和能量相关,不同波长光的靶色基包括细胞色素C氧化酶、视蛋白、卟啉等,而光的功率密度、光斑大小、能量密度等参数决定了光的能量。目前已有较多体内外研究证实了光生物调节作用在多种皮肤疾病治疗中的应用潜能。

Photobiomodulation,also known as photochemical modulation,refers to the use of low-power light from various sources to induce photophysical and photochemical modulation without thermal injury in the body.Photobiomodulation is related to the wavelength and energy of light.Target chromophores for light of different wavelengths include cytochrome C oxidase,opsin,porphyrin,etc.,and the parameters such as power density,spot size,and energy density determine the energy of light.At present,many in vivo and in vitro studies have confirmed the application potential of photobiomodulation in the treatment of various skin diseases.