缺血性脑血管病出院患者用药依从性现状及影响因素研究

Study on current status and influencing factors of medication adherence in discharged patients with ischemic cerebrovascular disease

目的探讨缺血性脑血管病出院患者的用药依从性现状及其影响因素。方法选取缺血性脑血管病出院患者360例。收集患者的一般资料、疾病及用药情况、用药知识水平,使用Morisky用药依从性问卷、一般自我效能、领悟社会支持表等资料,分析用药依从性现状及其影响因素。结果缺血性脑血管病出院患者的用药依从率为23.2%。依从性好和依从性差者文化程度、是否患有慢性病、对疾病的重视程度、每日用药频次、近2周用药是否出现不良反应、用药知识总分和领悟社会支持得分差异有统计学意义(P<0.05)。多因素回归分析结果显示,对疾病的重视程度、领悟社会支持得分是缺血性脑血管病出院患者用药依从性的影响因素(P<0.05)。结论缺血性脑血管病出院患者的用药依从性现状不容乐观,对疾病的重视程度、社会领悟支持是患者用药依从性的重要影响因素。

Objective To analyze the current status and influencing factors of medication adherence in discharged patients with ischemic cerebrovascular disease.Methods A total of 360 discharged patients with ischemic cerebrovascular disease were selected.The patients′general information,disease and medication status,and medication knowledge level were collected,and Morisky questionnaire on medication compliance,general self-efficacyscale(GSES),perceived social support scale(PSSS)and other data were used to analyze medication compliance status and its influencing factors.Results The medication compliance rate of discharged patients with ischemic cerebrovascular disease was 23.2%.There were significant differences in patients with good medication compliance and those with poor medication compliance with respect to education level,chronic disease,attention to disease,frequency of medicine use,adverse drug reactions after medication in the past two weeks,total score of medicine use knowledge and perceived social support score were the influencing factors of medication adherence(P<0.05).Multivariate regression analysis showed that the degree of attention to the disease,perceived social support were influencing factors for medication compliance in discharged patients with ischemic cerebrovascular disease(P<0.05).Conclusion The status of medication compliance in discharged patients with ischemic cerebrovascular disease is not optimistic.The degree of attention to the disease and perceived social support are the important factors affecting the medication compliance of patients with ischemic cerebrovascular disease.