基于复合灵敏度编码的高分辨率磁共振扩散成像原理及其临床应用

Principle and clinical application of high resolution magnetic resonance diffusion imaging with multiplexed sensitivity encoding

通过结合扩散加权成像(diffusion weighted imaging,DWI)和复合灵敏度编码(multiplexed sensitivity-encoding,MUSE)来校正回波平面成像中运动引起的相位变化,基于MUSE的高分辨率扩散成像(multiplexed sensitivity-encoding diffusion-weighted imaging,MUSE-DWI)能够最大限度地降低图像变形、减少磁敏感伪影,提高成像质量。与传统DWI相比,MUSE-DWI具有改进的矩阵反演条件、更好的信噪比以及更高的空间分辨率。目前,MUSE算法通过联合多种MRI技术进一步提高了成像质量,并且已经在多个领域得到广泛应用。本文就MUSE成像技术、MUSE基本原理、多技术联合MUSE成像,以及MUSE-DWI的临床应用做出简要的介绍。

By combining conventional diffusion-weighted imaging(DWI)and multiple sensitivity encoding(MUSE)to correct random motion-induced phase variations,multiplexed sensitivity-encoding diffusion-weighted imaging(MUSE-DWI)can minimize image distortion,milder susceptibility artifacts and improve imaging quality in echo-planar imaging.Compared with traditional diffusion-weighted imaging,MUSE-DWI has improved matrix inversion conditions,better signal-to-noise ratio and higher spatial resolution.So far,the multiplexed sensitivity-encoding algorithm has improved imaging quality by integrates multiple magnetic resonance imaging(MRI)techniques and has been widely used in multiple organs.In this paper,we introduced some aspects including MUSE imaging technology,the basic principle of MUSE,multi-technology combined MUSE,clinical application of MUSE-DWI briefly.