心脏磁共振评估左心室机械不同步的研究进展

Progress of cardiac magnetic resonance in assessment of left ventricular mechanical dyssynchrony

左心室机械不同步(left ventricular mechanical dyssynchrony,LVMD)是左心室运动异常的表现之一,而LVMD的相关测量指标是左心室应变的衍生指标,能够预测急性心肌梗死患者的预后和心脏再同步治疗的应答率。诊断LVMD的前提是精确测量左心室各节段的应变值,心脏磁共振(cardiac magnetic resonance,CMR)作为一项新兴的心脏影像学检查手段,能够准确测量左心室各节段的应变值。有很大的临床和科研价值。该文对LVMD的发生机制、CMR对LVMD指标的测量以及CMR所测量的LVMD指标在心脏疾病诊疗中的临床应用做一综述。

Left ventricular mechanical dyssynchrony(LVMD)is one of the manifestations of abnormal left ventricular motion.And the measured indexes related to LVMD are the indexes derived from left ventricular strain,which can predict the response to cardiac resynchronization therapy and the prognosis of the patients with acute myocardial infarction.The premise of LVMD diagnosis is to measure segmental strains of left ventricle accurately.As an emerging cardiac imaging technology,cardiac magnetic resonance(CMR)can accurately measure the strain of each left ventricle segment,which makes it valuable in both clinic and scientific research.In this article,the mechanism of LVMD,the measurement by CMR and its clinical application to heart diseases are reviewed.