我院新冠肺炎疫情期间发热门诊隔离区用药处方及抗菌药物使用情况分析

Analysis of Drug Prescriptions and Use of Antimicrobial Agents in the Isolation Area of Fever Clinic in Our Hospital during COVID-19 Pandemic

目的:分析我院新冠肺炎(COVID-19)疫情期间发热门诊隔离区用药处方及抗菌药物的使用情况,为发热门诊隔离区的药品供应及抗菌药物的应用提供参考。方法:收集我院COVID-19疫情期间发热门诊隔离区用药处方,依据卫生行政部门制定的处方评价表进行分析,采用WHO推荐的限定日剂量(DDD)分析法,结合药物利用指数(DUI)对含抗菌药物的处方进行统计和分析。结果:COVID-19疫情期间,我院发热门诊隔离区患者所用药品共5类15种,以抗感染、抗病毒、解热镇痛类药物为主,其中抗菌药物共6种,使用频次占比为43.89%;发热门诊隔离区处方的抗菌药物使用率为56.07%,无抗菌药物联合应用情况;其中DUI≤1的抗菌药物4种,占比66.67%,DUI>1的抗菌药物2种,占比33.33%。结论:COVID-19疫情期间,发热门诊隔离区建议至少配备抗感染、抗病毒、解热镇痛、消化系统用药等药物。我院COVID-19疫情期间发热门诊隔离区抗菌药物的联合使用情况、DDDs、DUI均在较为合理的范围,但存在抗菌药物使用率偏高、选择倾向大及超剂量使用的情况,故建议临床医生在药物治疗过程中合理使用药物,同时做好药学监护,以保证患者用药安全。

Objective:To analyze the drug prescriptions and use of antimicrobial agents in the isolation area of fever clinic in our hospital during COVID-19 pandemic,and to provide reference for the drug supply and use of antimicrobial agents in the isolation area of fever clinic.Methods:The drug prescriptions in the isolation area of fever clinic in our hospital during COVID-19 pandemic were collected and analyzed according to the prescription evaluation table developed by the health administrative department.The defined daily dose(DDD)method recommended by WHO and drug utilization index(DUI)were used to statistically analyze the prescriptions containing antimicrobial agents.Results:During the COVID-19 pandemic,15 kinds of drugs in 5 categories were used in the isolation area of fever clinic in our hospital,which inclued 6 kinds of antimicrobial agents.The use frequency of antimicrobial agents accounted for 43.89%.The usage rate of antimicrobial agents in the isolation area of fever clinic was 56.07%,and no combined use of antimicrobial agents.There were 4 kinds of antimicrobial agents with DUI≤1,accounting for 66.67%.There were 2 kinds of antimicrobial agents with DUI>1,accounting for 33.33%.Conclusion:During COVID-19 pandemic,it is recommended that at least anti-infection,antiviral,antipyretic and analgesic,and digestive system drugs should be equipped in the isolation area of fever clinic.The combined use,DDDs and DUI of antimicrobial agents in the isolation area of fever clinic in our hospital during COVID-19 pandemic were in a reasonable range,however,the usage rate and the tendency of selecting antimicrobial agents were relatively high,and overdose use of antimicrobial agents existed.Therefore,it is suggested that clinicians should use drugs rationally in the process of drug therapy,and pharmaceutical care should be conducted to ensure safe medication for the patients.