探讨宫颈浸润癌发病人群的临床特征

Investigation about the clinical characteristics of patients with invasive cervical cancer

目的探讨目前宫颈浸润癌发病人群的临床特征,为宫颈浸润癌的预防提供理论依据。方法回顾性收集了2016年1月-2021年3月在克拉玛依市中心医院诊治的宫颈浸润癌137例,就不同年龄段患者的结婚年龄、结婚次数、孕产次、分娩方式、文化程度、就诊原因、临床分期、病理组织类型及高危型HPV感染等特征进行分析。结果137例宫颈浸润癌患者的平均年龄为(46.5±19.09)岁,行宫颈癌筛查的17例,有临床症状就诊的120例;子宫颈鳞癌114例,子宫颈腺癌17例,其他病理类型6例;≤44岁、45~59岁、≥60岁患者的结婚年龄、产次、流产次数、分娩方式、就诊原因及文化程度比较,差异有统计学意义(P<0.05);结婚次数、孕次、临床分期、病理类型及高危HPV亚型感染差异无统计学意义(P>0.05)。结论宫颈浸润癌患者大部分为出现临床症状后才就诊的人群,老年患者尤为明显,重视规范的宫颈癌筛查对预防宫颈浸润癌尤为重要。

Objective To investigate the clinical characteristics of patients with invasive cervical cancer,and to provide theoretical basis for the prevention of invasive cervical cancer.Methods A total of 137 cases of cervical invasive cancer treated in central hospital of Karamay from January 2016 to March 2021 were retrospectively collected.The characteristics of patients in different age,such as age for marriage,number of marriage,times for pregnancy and childbirth,mode of delivery,educational level,and reason for medical treatment,clinical stage,pathological histological type and high-risk HPV infection were analyzed.Results The average age of 137 patients with invasive cervical cancer was(46.55±19.09)years old.17 cases were given cervical cancer screening,120 cases had clinical symptoms.There were 114 cases undergoing cervical squamous cell carcinoma,17 cases with cervical adenocarcinoma and 6 cases belonging to other pathological types.There were significant differences in marriage age,times of labor,times of abortion,mode of delivery,reasons for medical treatment and educational level among patients aged≤44,45-59 and≥60 years(P<0.05).There were no significant differences in marriage times,pregnancy times,clinical stage,pathological type and high-risk HPV subtype infection(P>0.05).Conclusions The majority of patients with cervical invasive cancer will see doctor only when clinical symptoms appear,especially in elderly patients.It is particularly important to pay attention to the standardized cervical cancer screening for the prevention of cervical invasive cancer.