我院住院患儿口服药品分剂量调查分析

Drug Manipulation for Pediatric Oral Dosing in Our Hospital

目的:探讨我院儿童住院患者口服药品分剂量使用现状,为保障儿童合理安全用药提供参考。方法:抽取我院2018年6月至2019年5月儿童口服药品分剂量用药医嘱,统计分析分剂量药品信息,包括患儿年龄、性别、药品名称、规格、拆分剂量等。结果:共纳入1080例患儿,15724条医嘱,其中泌尿系统药物分剂量医嘱数占比最多(4282条,27.23%),其次为影响变态反应和免疫功能药物(2202条,14.00%)、消化系统药物(2149条,13.67%)及抗感染药物(1403条,8.92%)。片剂分剂量占比最多(10434条,66.36%),其次为硬胶囊(1329条,8.45%)及口服溶液剂(739条,4.70%)。结论:我院现有规格无法满足临床需求,普遍存在的儿童分剂量用药现象,为儿童安全用药带来极大隐患,需由国家、企业及医院共同协作以保障儿童合理安全用药。

Objective:To probe into the application status of drug manipulation for pediatric oral dosing in our hospital,so as to provide reference for ensuring the rational and safe medication of children.Methods:Medical orders of drug manipulation for pediatric oral dosing were extracted from Jun.2018 to May 2019 in our hospital,and the drug information of manipulation for pediatric oral dosing was statistically analyzed,including age,gender,drug name,specification and manipulation dose.Results:A total of 1,080 children were enrolled,with 15,724 medical orders,among which the medical orders of urinary system with drug manipulation for pediatric oral dosing accounted for the largest proportion(4,282 entries,27.23%),followed by drugs affecting allergy and immune function(2,202 entries,14.00%),digestive drugs(2,149 entries,13.67%)and anti-infective drugs(1,403 entries,8.92%).Tablets accounted for the largest number of drug manipulation for pediatric oral dosing(10,434 entries,66.36%),followed by hard capsules(1,329 entries,8.45%)and oral solutions(739 entries,4.70%).Conclusion:The existing specifications of our hospital cannot meet the clinical needs,and the prevalent phenomenon of drug manipulation for pediatric oral dosing poses a great danger to the medication safety,which requires the collaboration of the state,enterprises and hospitals to ensure the rational and safe medication for children.