基于乙硫基取代的三层酞菁铕二聚体修饰ITO电极构筑电化学多巴胺和尿酸传感器

Fabrication of Electrochemical Sensor for Dopamine and Uric Acid Based on a Novel Dimeric Phthalocyanine-involved Quintuple-decker Modified Indium Tin Oxide Electrode

通过在水平和垂直两个方向上来扩展酞菁配合物的共轭结构,合成了三明治三层酞菁铕二聚体配合物[Pc(SC_(2)H_(5))_(8)]_(2)Eu_(2)[BiPc(SC_(2)H_(5))_(12)]Eu_(2)[Pc(SC_(2)H_(5))_(8)]_(2),使用Quasi-Langmuir-Shäfer(QLS)方法将配合物薄膜修饰在氧化铟锡导电玻璃(ITO)电极表面,利用多种谱学手段对配合物分子在薄膜内的排列进行表征,发现分子采取J聚集模式Edge-on排列在ITO电极表面,该薄膜具有良好的半导体性质,导电率高达8.86×10^(−5)S/cm.将配合物薄膜修饰的ITO电极成功应用于多巴胺(DA)和尿酸(UA)的电化学灵敏检测,最低检测限分别达到1.35和1.64μmol/L,灵敏度分别达到110和186.5 mA·μL·mol^(−1)·cm^(−2).

Combination between the extendingπ-conjugated system in the longitudinal and transverse directions of Pc macrocycles,sandwich-type ethylthio substituted phthalocyaninato europium complex[Pc(SC_(2)H_(5))_(8)]_(2)Eu_(2)[BiPc(SC_(2)H_(5))_(12)]Eu_(2)[Pc(SC_(2)H_(5))_(8)]_(2)was synthesized.The self-assembled film of the complex was prepared by means of the solution-based Quasi-Langmuir-Shafer(QLS)method.The molecular arrangement of the complex in the film was characterized by various spectroscopic methods.It was found that the molecules of the complex in the film were arranged on the substrate surface in the J-aggregation mode and edge-on configuration.The film was revealed to be a good semiconductor with conductivity as high as 8.86×10^(−5)S/cm.ITO electrode modified by the QLS film of the com⁃plex was successfully applied in electrochemical detection,resulting in sensitive detection of dopamine(DA)and uric acid(UA)with the good sensitivities of 110 and 185.6 mA·μL·mol^(−1)·cm^(−2)and low detection limits of 1.35 and 1.64μmol/L for DA and UA,respectively.