2017—2020年辽阳市中心医院输血患者不规则抗体结果调查情况分析

Analysis of irregular antibody results of blood transfusion patients in Liaoyang Central Hospital from 2017 to 2020

目的了解辽阳市中心医院输血患者不规则抗体筛查阳性结果的分布特征,探寻促进临床安全有效的用血措施。方法选取2017年1月至2020年12月辽阳市中心医院收治的14235例输血患者作为研究对象,统计其不规则抗体筛查及抗体鉴定结果,对不规则抗体的种类及分布特点做统计分析。结果不规则抗体筛查阳性率为0.76%(108/14235)。女性患者的阳性检出率高于男性患者的阳性检出率,差异有统计学意义(P<0.05);其中Rh系统的抗体最多达93例,占比为86.11%(93/108);输血频次>3次的患者不规则抗体阳性率高于输血次数≤3次的患者,差异有统计学意义(P<0.05)。结论反复输血的患者及女性患者不规则抗体筛查阳性率偏高,对于需要反复输血的患者及女性患者建议给予Rh同型输血以可减少不规则抗体的产生,提高输血安全。

Objective To comprehend the distribution characteristics of the positive results of irregular antibody screening in blood transfusion patients in Liaoyang Central Hospital,and to explore the measures to promote clinical safe and effective blood use.Methods A total of 14235 blood transfusion patients admitted to Liaoyang Central Hospital from January 2017 to December 2020 were selected as the study subjects,and the irregular antibody screening and antibody identification results were counted,and the types and distribution characteristics of irregular antibodies were analyzed.Results The positive rate of irregular antibody screening was 0.76%(108/14235).The positive rate of female patients was higher than that of male patients,and the difference was statistically significant(P<0.05).Among them,Rh system antibody reached 93 cases at most,accounting for 86.11%(93/108).The positive rate of antibody in patients with more than 3 blood transfusions was higher than that in patients with less than 3 blood transfusions,and the difference was statistically significant(P<0.05).Conclusion The positive rate of irregular antibody screening in patients with repeated blood transfusion and female patients is on the high side.Therefore,it is recommended to give Rh homotype blood transfusion to patients with repeated blood transfusion,so as to reduce the production of irregular antibody and improve the safety of blood transfusion.