3D打印海藻酸钠基功能材料的研究进展

Sodium Alginate-based Functional Materials for 3D Printing

海藻酸钠优良的生物相容性和生物可降解性赋予其在生物医药领域广阔的应用前景,如何实现利用海藻酸钠制造生物医用材料、组织、器官成为推动其优良性能在生物医学上应用的重要挑战之一。3D打印技术拥有对结构的可控设计和材料的高利用率的优点,在生物材料的个性化定制加工方面具有独特的优势。本文介绍了海藻酸钠的性质特点,并综述了3D打印海藻酸钠基材料在组织工程以及肿瘤药物筛选模型等方面的最新应用,最后作出了总结与展望。

The excellent biocompatibility and biodegradability of sodium alginate give it wide applications in the field of biomedicine.How to use sodium alginate to manufacture biomedical materials,tissues and organs has become one of the important challenges to promote its excellent performance in medical applications.3 D printing technology gets the advantages of controllable design of structure and high utilization rate of materials,which can realize personalized manufacturing.In this paper,the latest applications of 3 D printing sodium alginate based materials in bone tissue engineering scaffolds,artificial blood vessels,in vitro construction of tumor models,artificial organs and other aspects in tissue engineering were discussed and prospected.