植物多酚缓解运动疲劳作用机制研究进展

Research Progress on the Mechanism of Plant Polyphenols of Alleviating Exercise Fatigue

疲劳是机体能量协调紊乱产生的现象,长时间运动疲劳会引发相关的疾病。多酚具有明显的生物活性,如抗氧化、抗肿瘤等。目前多酚已被证实具有抗疲劳作用,可通过调节AMPK信号通路调节氧化应激、能量代谢和炎症以及底物代谢发挥缓解运动疲劳的功效。本文对运动疲劳产生及机制、抗疲劳多酚类物质的来源及其缓解疲劳的作用机制进行了系统综述,旨在为多酚类物质的抗疲劳功能食品的研发提供参考。

Fatigue is a phenomenon caused by the disorder of energy coordination in the body,and prolonged exercise fatigue will lead to related diseases.Polyphenols have obvious biological activities,such as anti-oxidation,anti-tumor and so on.At present,polyphenols have been proved to have anti-fatigue effect,which can relieve exercise fatigue by regulating the AMPK signaling pathway to regulate oxidative stress,energy metabolism and inflammation,as well as substrate metabolism.In this paper,the generation and mechanism of exercise fatigue,the source of anti-fatigue polyphenols and the action mechanism of anti-fatigue polyphenols are systematically reviewed in order to provide reference for the research and development of anti-fatigue functional foods with polyphenols.