肢端肥大症并发高血压患者的心脏彩超表现

Cardiac color Doppler ultrasonography findings in patients with acromegaly complicated with hypertension

目的探讨肢端肥大症并发高血压患者的心脏彩超表现。方法选取中山大学孙逸仙纪念医院2013年1月至2018年12月住院治疗的30例确诊为肢端肥大症的患者为研究对象,将其中并发高血压的15例患者作为研究组,未并发高血压的15例患者作为对照组。比较两组的实验室指标及心脏彩超检查结果,分析肢端肥大症患者心脏扩大的影响因素。结果研究组生长激素水平低于对照组,差异有统计学意义(P<0.05)。研究组升主动脉内径、左心室后壁厚度、室间隔厚度大于对照组,差异有统计学意义(P<0.05);两组主动脉根部内径、左心室舒张末期内径、右心室舒张末期内径、左心房内径、射血分数比较,差异无统计学意义(P>0.05)。高血压是肢端肥大症患者心脏扩大的影响因素(P<0.05)。结论通过心脏彩超检查能够了解肢端肥大症并发高血压患者的心脏结构及功能改变情况,指导临床治疗。有效控制高血压对于降低肢端肥大症患者心脏结构和功能损伤的发生风险有重要意义。

Objective To explore the cardiac color Doppler ultrasonography findings in patients with acromegaly complicated with hypertension.Methods A total of 30 patients with acromegaly were selected from Sun Yat-sen Memorial Hospital, Sun Yat-sen University from January 2013 to December 2018,among which the 15 patients complicated with hypertension were taken as the study group, and 15 patients without hypertension were taken as the control group.Compared the laboratory indexes and cardiac color Doppler ultrasound examination results of the two groups.Analyzed the influencing factors of cardiac dilatation in patients with acromegaly.Results The growth hormone level in the study group was lower than that in the control group, and the difference was statistically significant(P<0.05).The diameter of ascending aorta, the thickness of left ventricular posterior wall and the thickness of ventricular septum in the study group were significantly higher than those in the control group, and the differences were statistically significant(P<0.05).There was no significant difference between the two groups of aortic root diameter, left ventricular end diastolic diameter, right ventricular end diastolic diameter, left atrial diameter and ejection fraction(P>0.05).Hypertension was an influencing factor of cardiac dilatation in patients with acromegaly(P<0.05).Conclusion The cardiac color Doppler ultrasound examination can understand the changes in cardiac structure and function of patients with acromegaly complicated with hypertension, and guide clinical treatment.Effective control of hypertension is of great significance for reducing the risk of cardiac structure and function damage in patients with acromegaly.