增材制造个性化骨增量钛网的工程实现

Engineering realization of customized titanium mesh for bone regeneration by additive manufacturing

目的阐述个性化骨增量钛网的增材制造研发和生产工艺流程,确保质量可靠且一致性的钛网成品进入临床手术。方法采用有限元分析的方法优化个性化骨增量钛网的设计,使用医用纯钛金属材料增材制造个性化骨增量钛网及随炉试样,对试样做理化性能测试来评估个性化骨增量钛网的性能。结果在水平、垂直和45°方向增材制造试样的屈服强度平均值分别为372.5 MPa、414.8 MPa和400.3 MPa,断裂延伸率平均值分别为28.2%、24.0%和28.7%;试样的组织致密度平均值为99.89%;表面粗糙度(Ra)为8μm(水平向)和13μm(垂直向)。结论个性化骨增量钛网经过设计和仿真、增材制造和后处理后可以获得满足临床应用要求的性能,其临床上的长期有效性有待钛网植入后进一步的随访观察。

Objective Explain R&D and production workflow for customized titanium mesh by additive manufacturing,to ensure high quality and consistency before titanium mesh comes to clinical surgery.Methods Design of customized titanium mesh is optimized by finite element analysis.Titanium mesh and test coupons are additively manufactured using medical-level pure titanium powder.The test results of test coupons are used to evaluate the mechanical performance of titanium mesh.Results Yield strength of test coupons printed horizontally,vertically,and 45 degrees are 372.5 MPa,414.8 MPa,and 400.3 MPa;Elongation rates are 28.2%,24.0%,and 28.7%;Average relative density is 99.89%;Surface roughness is Ra 8μm(horizontal)and 13μm(vertical).Conclusion Customized titanium mesh has acceptable performance for clinical surgery by optimized workflow:CAD,CAE,additive manufacturing,and post-processing.A long-term study on clinical effectiveness is required after customized titanium mesh is successfully implanted.