血小板-淋巴细胞比率和中性粒细胞-淋巴细胞比率对于缺血性肠病预后的判断

Value of platelet-lymphocyte ratio and neutrophil-lymphocyte ratio in predicting the prognosis of ischemic bowel disease

[目的]研究缺血性肠病患者的血液学参数血小板/淋巴细胞比率(PLR)和中性粒细胞-淋巴细胞比率(NLR)的预后判断价值。[方法]选取接受住院治疗的缺血性肠病的老年患者39例,将其血常规资料进行统计分析。记录并比较患者入院时、入院第4天或者第5天(治疗中)以及出院时的白细胞计数(WBC)、平均血小板体积(MPV)、中性粒细胞计数(NEU)、血小板计数(PLT)、淋巴细胞计数(LYMP)。计算并评价PLR、NLR。[结果]患者在入院时与治疗中各参数的比较中,只有LYMP显示出统计学差异(P=0.007);而在治疗中与出院时的各参数比较中,均未显示出统计学差异;而在入院时与出院时的比较中,除了PLT差异不明显(P=0.189),其余均差异有统计学意义;有序多分类Logistic回归分析结果显示,LYMP、PLR、NLR均为缺血性肠病的预后判断的影响因素;ROC曲线分析结果显示,WBC、LYMP、PLR、NLR对于缺血性肠病的预后判断均有价值,曲线下面积分别为WBC 0.309;LYMP 0.401;PLR 0.681;NLR 0.781.[结论]对于缺血性肠病患者,PLR和NLR对其预后判断具有一定价值。

[Objective]To explore the prognostic value of platelet/lymphocyte ratio(PLR)and neutrophil-lymphocyte ratio(NLR)in patients with ischemic bowel disease.[Methods]A total of 39 elderly patients with ischemic bowel disease who received inpatient treatment were selected,their blood routine data were statistically analyzed and recorded,and the indicators of the 4 th or 5 th day of admission(in treatment)were compared.White blood cell count(WBC),mean platelet volume(MPV),neutrophil count(NEU),platelet count(PLT),lymphocyte count(LYMP)were calculated and evaluated at discharge.[Results]In the comparison of the parameters on admission and treatment,only the LYMP showed statistical difference(P=0.007).However,there was no statistical difference in the comparison of the parameters between the treatment and the discharge.In the comparison between admission and discharge,there was no significant difference in platelet count(P=0.189),the rest were statistically significant.The Logistic regression analysis showed that LYMP,PLR and NLR were the influencing factors of ischemic bowel disease.The results of ROC curve analysis showed that WBC,LYMP,PLR and NLR,were valuable in predicting the prognosis of ischemic bowel disease.The AUC was WBC 0.309;LYMP 0.401;PLR 0.681;NLR 0.781.[Conclusion]For patients with ischemic bowel disease,PLR and NLR have certain value in judging the prognosis of ischemic bowel disease.