康复理疗仪联合盐酸舍曲林治疗抑郁症伴失眠患者的疗效研究

Effect of rehabilitation physiotherapy instrument combined with sertraline hydrochloride tablets in the treatment of depression with insomnia

目的研究康复理疗仪辅助治疗抑郁症伴失眠患者的临床疗效。方法选取62例抑郁症伴失眠的住院患者,按照随机数字表法分为常规治疗组30例,观察组32例,两组病人均给予盐酸舍曲林片治疗,在此基础上观察组每日加用康复理疗仪辅助治疗,观察治疗8周后两组病人汉密尔顿抑郁量表(HAMD)评分、匹兹堡睡眠质量指数(PSQI)评分的变化。结果治疗前,两组患者的抑郁量表评分和睡眠质量对比无统计学差异。治疗后,在抑郁情绪改善方面,两组患者HAMD评分差异无统计学意义(P>0.05)。在睡眠改善方面,观察组PSQI评分较常规治疗组差异有统计学意义(P<0.05)。观察组的不良反应总发生率(12.5%)与常规治疗组(16.7%)比较,差异无统计学意义(P>0.05)。结论康复理疗仪可以改善抑郁症伴失眠患者的睡眠质量,且安全无副作用,值得临床推广使用。

Objective To observe the clinical effect of rehabilitation physiotherapy instrument in the treatment of depression with insomnia.Method.Methods 62 inpatients with depression and insomnia were randomly divided into conventional treatment group(n=30)and observation group(n=32).Patients in both groups were given sertraline hydrochloride tablets orally.On this basis,rehabilitation physiotherapy instrument was added to the observation group every day.After 8 weeks of treatment,the Hamilton Depression Scale(Hamilton Depression Scale,HAMD)score and Pittsburgh sleep quality index(Pittsburgh sleep quality index,PSQI)score of the two groups were observed.Results Before treatment,there was no significant difference in depression index and sleep quality between the two groups.After treatment,there was no significant difference in HAMD score between the two groups(P>0.05).In terms of sleep improvement,the PSQI score of the observation group was significantly different from that of the conventional treatment group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the observation group(12.5%)and the conventional treatment group(16.7%)(P>0.05).Conclusion Rehabilitation physiotherapy instrument can improve the sleep quality of patients with depression and insomnia,and has the characteristics of safety without side effects and comfortable experience,which is worthy of clinical application.