加减寿胎丸治疗脾肾两虚型先兆流产合并宫腔积液的临床刍议

Clinical Opinion on Add and substract Life of fetal pill in Treating Threatened Abortion with Uterine Effusion due to Deficiency of Spleen and Kidney

目的浅析加减寿胎丸治疗脾肾两虚型先兆流产合并宫腔积液的临床效果。方法随机选取2020年1月—2021年5月该院门诊60例脾肾两虚型先兆流产合并宫腔积液患者,随机分为对照组(黄体酮治疗)、观察组(加减寿胎丸联合黄体酮治疗)各30例,观察两组治疗效果、β-HCG、P指标、宫腔积液面积、中医证候评分的变化情况。结果观察组总有效率为96.67%,对照组66.67%,观察组较对照组疗效更佳,差异有统计学意义(χ^(2)=9.017,P<0.05);两组β-HCG、P指标均较治疗前上升,宫腔积液面积均缩小,且观察组优于对照组,差异有统计学意义(P<0.05);从中医证候积分来看,观察组治疗后积分降低更显著,差异有统计学意义(t=2.191、2.029、2.127、2.114、2.564,P<0.05)。结论联合加减寿胎丸在改善脾肾两虚型先兆流产合并宫腔积液患者的血清指标、缩小宫腔积液面积、减轻临床症状上,优于单用黄体酮,加减寿胎丸值得临床应用、推广。

Objective To analyze the clinical effect of Add and substract Life of fetal pill in the treatment of threatened abortion with spleen and kidney deficiency combined with uterine effusion.Methods From January 2020 to May 2021,60 patients with threatened abortion due to deficiency of both spleen and kidney and uterine effusion were randomlyselected from the outpatient department of this hospital,and they were randomly divided into control group(progesterone treatment)and observation group(add and substract Life of fetal pill combined progesterone treatment),30 cases for each.The treatment effect,β-HCG,P index,uterine effusion area,TCM syndrome score changes of two group were observed.Results The total effective rate of the observation group was 96.67%and that of the control group was 66.67%.The observation group had better curative effect than the control group,and the difference was statistically significant(χ^(2)=9.017,P<0.05);theβ-HCG and P indexes of the two groups were higher than before treatment,and the area of uterine effusion was reduced,and the observation group was better than the control group,and the difference was statistically significant(P<0.05);from the perspective of TCM syndrome scores,the observation group scores decreased more significantly,and the difference was statistically significant(t=2.191,2.029,2.127,2.114,2.564,P<0.05).Conclusion The combination of Add and substract Life of fetal pill is better than progesterone alone in improving the serum indexes of patients with threatened abortion of spleen and kidney deficiency combined with uterine effusion,reducing the area of uterine effusion and reducing the clinical symptoms.It is worthy of clinical application and promotion.