中药内服外治综合疗法治疗糖尿病周围神经病变气虚血瘀证患者的效果探讨

Study on the Effect of the Comprehensive Therapy of Chinese Medicine Taken Orally and Externally on the Treatment of Diabetic Peripheral Neuropathy Patients with Qi Deficiency and Blood Stasis Syndrome

目的探究与分析中药内服外治综合疗法治疗糖尿病周围神经病变气虚血瘀证患者的效果。方法采取随机数字表法对方便选取聊城市中医医院自2020年4月—2021年4月收治的糖尿病周围神经病变气虚血瘀证患者120例分组,各60例,对照组仅给予中药内服治疗,观察组在对照组基础上加用中药熏蒸、针灸疗法治疗,对比两组临床疗效、治疗前后中医证候积分、Toronto临床评分、正中神经及腓总神经的感觉神经、运动神经传导速度。结果对照组总有效率为80.00%,观察组总有效率为95.00%,观察组与对照组相比总有效率较高,差异有统计学意义(χ^(2)=6.171,P=0.013)。对照组治疗后中医证候积分、Toronoto评分分别为(16.33±2.70)分、(3.74±0.40)分,观察组治疗后中医证候积分、Toronoto评分分别为(6.98±1.75)分、(1.72±0.45)分,观察组治疗后与对照组治疗后相比中医证候积分及Toronto评分均较低,差异有统计学意义(t=22.509、25.988,P<0.05)。对照组治疗后正中神经感觉神经传导速度、腓总神经感觉神经传导速度、正中神经运动神经传导速、腓总神经运动神经传导速分别为(45.77±2.64)、(40.53±4.27)、(47.64±4.60)、(44.66±4.59)m/s,观察组治疗后正中神经感觉神经传导速度、腓总神经感觉神经传导速度、正中神经运动神经传导速、腓总神经运动神经传导速分别为(53.87±4.25)、(48.77±4.31)、(55.20±2.34)、(52.31±3.01)m/s,观察组治疗后与对照组治疗后相比正中神经及腓总神经的感觉神经、运动神经传导速度均较高,差异有统计学意义(t=12.540、10.520、11.347、10.796,P<0.001)。结论中药内服外治综合疗法治疗糖尿病周围神经病变气虚血瘀可减缓临床症状及体征,调节正中神经及腓总神经的传导速度。

Objective To explore and analyze the effect of traditional Chinese medicine on the treatment of diabetic peripheral neuropathy patients with Qi deficiency and blood stasis syndrome.Methods A random number table was used to group conveniently selected 120 diabetic peripheral neuropathy patients with Qi deficiency and blood stasis syndrome admitted to Liaocheng Hospital of Traditional Chinese Medicine from April 2020 to April 2021,with 60 cases in each group.The control group was only given oral treatment with traditional Chinese medicine.The observation group was treated with traditional Chinese medicine fumigation and acupuncture on the basis of the control group.The clinical efficacy,TCM syndrome scores before and after treatment,Toronto clinical score,median nerve and common peroneal nerve sensory nerve and motor nerve conduction velocity were compared between the two groups.Results The total effective rate of the control group was 80.00%,and the total effective rate of the observation group was 95.00%.The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(χ^(2)=6.171,P=0.013).The scores of TCM syndromes and Toronto scores of the control group were(16.33±2.70)points and(3.74±0.40)points,respectively.The scores of TCM syndromes and Toronto scores of the observation group were(6.98±1.75)points and(1.72±0.45)points.The scores of TCM syndromes and Toronto scores in the observation group were lower than those in the control group after treatment,and the difference was statistically significant(t=22.509,25.988,P<0.001).After treatment in the control group,the median nerve sensory nerve conduction velocity,the common peroneal nerve sensory nerve conduction velocity,the median nerve motor nerve conduction velocity,and the common peroneal nerve motor nerve conduction velocity were(45.77±2.64)m/s and(40.53±4.27)m/s,(47.64±4.60)m/s,(44.66±4.59)m/s,the median nerve sensory nerve conduction velocity,common peroneal nerve sensory nerve conduction velocity,median nerve motor nerve conduction velocity,common peroneal nerve,motor nerve conduction velocities in the observation group after treatment were(53.87±4.25)m/s,(48.77±4.31)m/s,(55.20±2.34)m/s,(52.31±3.01)m/s,the sensory and motor nerve conduction velocities of the median nerve and common peroneal nerve in the observation group were higher than those in the control group after treatment,and the difference was statistically significant(t=12.540,10.520,11.347,10.796,P<0.001).Conclusion The treatment of diabetic peripheral neuropathy with Qi deficiency and blood stasis can slow down the clinical symptoms and signs,and regulate the conduction velocity of the median nerve and common peroneal nerve.