自身免疫性肝炎诊断和治疗指南(2021)

Guidelines on the diagnosis and management of autoimmune hepatitis(2021)

自身免疫性肝炎(autoimmune hepatitis,AIH)患者的临床特点包括血清氨基转移酶水平升高、高免疫球蛋白G血症、血清自身抗体阳性,肝组织学上存在中重度界面性肝炎等。早期诊断和恰当治疗可显著改善AIH患者的生存期和生活质量,减轻社会医疗负担。《自身免疫性肝炎诊断和治疗共识(2015)》在规范我国AIH的诊断和治疗方面发挥了积极作用。在此基础上,2021年底中华医学会肝病分会组织有关专家结合最新进展制定本部指南,旨在进一步提高我国AIH诊治水平。

Autoimmune hepatitis(AIH)is characterized by elevated serum aminotransferase and immunoglobulin G levels,seropositive results for autoantibodies and moderate to severe interface hepatitis in histologic findings.It will be most helpful in improving survival and life quality,if patients are diagnosed in the early stage and treated appropriately,which also helps relieve social medical burdens.Chinese consensus on the diagnosis and management of autoimmune hepatitis(2015)has contributed to standardizing the diagnosis and treatment of AIH.On the basis of the first consensus,at the end of 2021,under the organization of Chinese Society of Hepatology,experts devise this guide with latest advances aiming to further improve the level of diagnosis and management of autoimmune hepatitis.