肉瘤样型肝细胞癌1例

A Case Report of Sarcomatoid Hepatocellular Carcinoma

肉瘤样癌,是含有癌性和肉瘤性成分的混合物。肉瘤样型肝细胞癌,是肝细胞癌的一种罕见亚型,易转移,预后较差。患者中年男性,因右上腹痛2周余入院,查体腹部膨隆,有压痛、无反跳痛,实验室检查甲胎蛋白明显增高,影像检查发现肝内多发占位。病理示肉瘤样型肝细胞癌,免疫组化示Vim(+),CK(灶性+)。

Sarcomatoid carcinoma is a mixture containing cancerous and sarcomatous components. Sarcomatoid hepatocellular carcinoma, a rare subtype of hepatocellular carcinoma, is prone to metastasis with a poor prognosis. The patient, a middle-aged male, was admitted to the hospital with right upper abdominal pain for more than 2 weeks. On examination, the abdomen was bulging with pressure pain and no rebound pain. The alpha-fetoprotein was significantly increased in laboratory examinations, and the imaging examination revealed multiple intrahepatic spaceoccupying. Pathology showed sarcomatoid hepatocellular carcinoma, and immunohistochemistry showed Vim(+) and CK(focal +).