聚醚醚酮植入矫正鼻唇沟凹陷的效果

Clinical outcomes of personalized PEEK prosthesis in correcting nasolabial fold depression

目的探讨个体化聚醚醚酮(polyetheretherketone,PEEK)植入体矫正鼻唇沟凹陷的临床效果。方法2019年1月至2021年1月,南京医科大学附属友谊整形外科医院整形外科要求改善鼻唇沟凹陷患者30例(男5例.女25例,年龄26〜52岁,平均36.3岁),术前行锥形束CT扫描及三维模拟.定制个体化PEEK植入体,术中植入定制的PEEK植入体。术后随访3〜12个月,比较术前和术后3个月及6个月的皱纹评分和满意度。结果30例患者术后鼻唇沟凹陷改善明显,术后无血肿、感染等并发症。随访未见假体移位、外露,效果稳定持久,皱纹评分术后3个月为(2.30±0.47)分,术后6个月为(2.17±0.38)分,较术前(4.03±0.67)分均明显降低,差异均有统计学意义(均P<0.05)。满意度评分术后3个月为(3.97±0.56)分.术后6个月为(4.23±0.57)分,较术前(1.70±0.60)分均明显增高,差异均有统计学意义(均P<0.05)。结论结合3D打印技术的个体化PEEK植入体在矫正鼻唇沟凹陷中效果明显,安全稳定,推荐临床应用。

Objective To investigate the clinical outcomes of personalized polyetheretherketone(PEEK)implant in the correction of nasolabial fold depression.Methods A total of 30 patients with nasolabial fold depression(5 males,25 females,aged 26 to 52 years»mean 36.3 years)admitted to the Affiliated Friendship Plastic Hospital of Nanjing Medical University who want to undergo nasolabial fold augmentation from January 2019 to January 2021.All patients underwent CBCT scan and three-dimensional simulation,the personalized PEEK implant was designed and produced with CAD/CAM technique,the personalized PEEK was implanted during the operation.The patients were followed up for 3-12 months,and the wrinkle score and satisfaction were compared before operation and 3 months and 6 months after operation.Results The depressions of nasolabial fold were significantly improved in all patients,and there were no complications such as hematoma and infection after operation.During the follow-up,there was no implant displacement or exposure,and the effect was stable and lasting.The scores of wrinkles at 3 months after operation(2.30±0.47)and 6 months after operation(2.17±0.38)were significantly lower than those before operation(4.03±0.67),and the scores of satisfaction were significantly higher than those before operation(P<0.05).The scores of satisfaction at 3 months after operation(3.97±0.56)and 6 months after operation(4.23±0.57)were significantly higher than those before operation(1.70±0.60).The difference was statistically significant(P<0.05).Conclusions 3D printing personalized PEEK prosthesis is effective in correcting nasolabial fold depression,and it is safe and stable,so it is recommended for clinical application.