复方芩兰口服液治疗RSV毛细支气管炎的疗效分析

Efficacy of Compound Qinlan Oral Liquid in the Treatment of RSV Bronchiolitis

目的探讨复方芩兰口服液治疗呼吸道合胞病毒(respiratory syncytial virus,RSV)毛细支气管炎对炎性因子、免疫功能及疗效的影响。方法随机将本院收治的80例RSV毛细支气管炎患儿纳入对照组(n=40)和治疗组(n=40),对照组给予止咳、祛痰和抗感染等常规治疗,同时使用孟鲁司特钠。治疗组在对照组基础上加用复方芩兰口服液,比较治疗前后两组患者免疫功能、炎性因子和临床治疗效果。结果治疗后两组炎性因子、免疫功能均有所改善,组间比较治疗组明显优于对照组(P<0.05);治疗组治疗总有效率为97.50%,显著高于对照组的82.50%(P<0.05)。治疗组不良反应发生率(20.00%)与对照组(17.50%)比较,差异无统计学意义(P>0.05)。结论复方芩兰口服液可改善RSV毛细支气管炎患儿免疫功能和炎性因子水平,提升临床治疗效果。

Objective To investigate the effect of Compound Qinlan Oral Liquid on inflammatory factors,immune function and curative effect in the treatment of respiratory syncytial virus(RSV)bronchiolitis.Methods A total of 80 children with RSV bronchiolitis admitted to our hospital were randomly divided into control group(n=40)and treatment group(n=40).The control group was given conventional treatment such as cough relieving,expectorant removing and anti-infection,while montelukast sodium was used.The treatment group was additionally given Compound Qinlan Oral Liquid on the basis of the control group,and the immune function,inflammatory factors and clinical therapeutic effects of the two groups were compared before and after treatment.Results After treatment,the inflammatory factors and immune function of the two groups were improved,and the treatment group was significantly better than the control group(P<0.05);the total effective rate of the treatment group was 97.50%,which was significantly higher than 82.50%of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the treatment group(20.00%)and the control group(17.50%)(P>0.05).Conclusion Compound Qinlan Oral Liquid can improve the immune function and inflammatory factor levels in children with RSV bronchiolitis,and enhance the clinical treatment effect.