^(18)F-FDG PET/CT双期显像和MRI检查在诊断结直肠癌肝转移的对比研究

Diagnostic performance comparison of ^(18)F-FDG PET/CT dual point imaging and MRI in the colorectal cancer liver metastases

目的比较^(18)F-脱氧葡萄糖(FDG)PET/CT双期显像和MRI增强检查在结直肠癌肝转移的诊断效能。方法收集37例结直肠癌伴肝结节患者,根据结节的病理或随访结果分为转移瘤组和良性组。全部病例进行18F-FDG PET/CT双期显像(常规显像、延迟显像)和肝脏MRI增强扫描,评价两种检查诊断结直肠癌肝转移的效能,比较转移瘤组和良性组病例PET/CT双期显像和MRI的诊断准确率。结果PET/CT双期显像在诊断结直肠癌肝转移的AUC均高于MRI检查(Z分别=4.44、2.93,P均<0.05),而常规显像与延迟显像之间的AUC比较,差异无统计学意义(Z=1.80,P>0.05)。转移瘤组病例PET/CT双期显像的准确率与MRI检查比较,差异均无统计学意义(χ^(2)分别=0.66、0.15,P均>0.05)。在良性组PET/CT双期显像的准确率明显高于MRI检查,差异均有统计学意义(P均<0.05),而常规显像和延迟显像间的诊断准确率比较,差异无统计学意义(P>0.05)。结论^(18)F-FDGPET/CT双期显像对结直肠癌肝转移的诊断效能高于MRI检查,PET/CT双期显像有助于提高结直肠癌肝转移诊断准确率。

Objective To compare the diagnostic performance of ^(18)F-FDG PET/CT dual point imaging and MRI in the colorectal cancer liver metastases.Methods Totally 37 cases of colorectal cancer with liver nodules were collected and divided into metastasis group and benign group confirmed by the pathology or followed results of liver lesions.All cases were performed ^(18)F-FDG PET/CT dual point imaging(conventional imaging and delay imaging)and liver MRI enhance-ment examination.The diagnostic performance between two examinations were evaluated,and the accuracy of PET/CT and MRI in metastasis group and benign group were compared.Results The area under curve(AUC)of PET/CT dual point imaging were significant higher than that of MRI(Z=4.44,2.99,P<0.05),there was no significant difference between PET/CT conventional imaging and delay imaging(Z=1.80,P>0.05).In metastasis group,there was no significant difference between PET/CT dual point imaging and MRI on diagnostic accuracy(χ^(2)=0.66,0.15,P>0.05).In benign group,the diagnostic accuracy of PET/CT dual point imaging were significant higher than that of MRI(P<0.05),there was no signif-icant difference between PET/CT conventional imaging and delay imaging(P>0.05).Conclusion The diagnostic effi-ciency of ^(18)F-FDG PET/CT dual point imaging is better than that of MRI,and PET/CT dual point imaging are contributed to improve the diagnostic accuracy in colorectal cancer liver metastases.